MSM Methyl-sulfonyl-methane

MSM is an organic sulfur compound found naturally in fruits, vegetables, in the grain and animals, including humans.
MSM is a compound solid soluble in water, also known as dimethyl sulfone-, and sulfonilbismetano-methyl sulfone, which is found in nature: in the oceans, algae and various forms of plankton absorb large quantities of sulfur from the water and turn them into an elemental form, with organic links. At the time of their death, the organic molecules of algae and planktonic organisms are decomposed by enzymatic processes that generate DMS, or dimethyl sulphide, a volatile compound and poorly water soluble. This is collected in the stratosphere, where, for the action of ultraviolet rays, is oxidized and converted first in DMSO (dimethylsulfoxide) and then in the MSM (methyl-sulfonyl-methane).

The body needs it for the construction of almost all the important molecules, ie enzymes, hormones, amino acids, antibodies, antioxidants. It gives the body one of the four basic minerals and is present in many of its main functions and in virtually every cell. The circulatory system of an adult man naturally MSM levels of about 0.2 mg / kg. Adult normal eject from 4 to 11 mg of MSM per day through the urine.
Several studies suggest that the systemic concentration of MSM decreases in mammals over the years, perhaps as a result of metabolic changes or changes in eating habits. With the shortage of sulfur, we are witnessing  irrigidimento of the muscles and ligaments, the crumpled skin, and reducing the elasticity of lung tissue and arterial blood vessels. Also terminates the transfer of genetic information through the soft connective tissue, so that typical diseases of old age are probably due to reduced communication between cells and tissues.

The nails and hair are made up mainly by a protein high in sulfur, the keratin.
Tissues such as flexible connective and cartilage contain proteins with sulfur bonds flexible. Collagen is the protein that is found in greater quantities in our bodies, as well as a main component of all connective tissues. It gives elasticity to skin by interacting with the fibers of another protein called elastin. In cartilage, the glucosamine, chondroitin and the proteoglycans, which contain sulfur, forming, together with collagen, a fibrous protein that forms the structure of collagen itself and makes it flexible.
Methyl-sulfonyl-methane (MSM) is a source of stable, naturally rich in sulfur. The sulfur is present in particularly high concentration in the joints where participating in the production of chondroitin sulfate, glucosamine and of hyaluronic. Has an important place in maintaining the stability and integrity of connective tissue and proteins, and also plays a key role in safeguarding the integrity of the joints and the elasticity of the connective tissue. In fact, sulfur is the main component of glycosaminoglycans and other major components of cartilage tissue. These substances form a kind of protective gel that works as a matrix for the tendons, cartilage, skin and bones.

Among the actions that are attributed to supplements of MSM there are those of pain, especially in arthritis, immune modulator in autoimmune diseases, muscle recovery, helps you sleep and the treatment of diabetes. A preliminary research also suggests some possible anti-cancer effects.

Numerous studies have shown the usefulness of integration of nutritional MSM in cases of osteoarthritis and rheumatoid arthritis. One study showed a reduction of 82% of arthritic pain in patients after six weeks of administration with 2.25 grams of MSM daily.
MSM is very effective in countering the inflammation caused by autoimmune reactions. Several studies have shown that the integration of MSM helps to reduce the degenerative alterations and inflammation of the joints to load.

MSM is also essential in many enzyme reactions and hormone, as for a proper functioning of the immune system. When the body is available in sufficient MSM seems to focus around the mucous membranes which creates a protective coating that reduces the effects of allergens and contaminants outside. Studies show that taking MSM has a beneficial effect in cases of asthma and allergy (food, contact, inhalation, etc.)..
The property of anti-MSM seems attributable to its ability to bind to the mucosa and form a natural protective interface between the guest and allergens. In addition, MSM relieve allergies detoxify the body, eliminating free radicals and improving the permeability of the cells. It's established a direct correlation between the concentration of MSM recruited and resistance to allergens. Several authors have pointed out that MSM, as inhibitor of histamine, it works at least as traditional antihistamines, but without the same result in side effects of antihistamines.

Some laboratory studies have shown that many types of skin diseases, often linked to allergies, respond positively to a diet supplemented with MSM. And 'demonstrated that administration of MSM orally is effective against acne, rosacea on the skin dry, scaly or irritated. When applied locally, in the form of gel or lotion, MSM is useful in treating skin disorders such as acne, psoriasis, eczema, dermatitis, dandruff, scabies, nappy rash and various fungal infections. Even the scars resulting from burns and the results are positive topical application: the healing of the wounds appear to be accelerated with MSM (especially when taken in conjunction with vitamin C).

Regular use of MSM may help maintain the health and appearance of the skin gradevole, nail and hair: MSM is required for the production of keratin and collagen.

MSM is considered synergistic for most vitamins and other nutrients such as vitamin C, coenzyme Q10, all B-complex vitamins, vitamin A, D and E, amino acids, selenium, calcium, magnesium, etc. .. MSM improves the intake of these nutrients to the cells, thus extending the life.

MSM is a powerful antioxidant, capable of impeding the action of free radicals, turning them off.
As the main source of sulfur, MSM is essential for the proper functioning of natural antioxidant mechanisms of our body. In neutralize free radicals, the body uses a variety of antioxidant enzymes which contain amino acids and sulfur compounds derived its structure and biological activity of sulfur bonds. In addition, MSM provides the sulfur necessary for the sulfur amino acids (methionine and cysteine taurine,) considered potent antioxidants.

We know that MSM is dissolved in several organic and inorganic compounds. Linked to the mucosa, MSM reacts with toxins, helping to disable and speeding deportation. Furthermore, increases the permeability of cell membranes, thus facilitating the intake of nutrients and waste disposal.

A study reveals that at least 75% of individuals taking one or more antacids or histamine drugs, against the acidity of the stomach, managed to substantially reduce or eliminate all those drugs, a week after starting to take MSM as a supplement diet. In another study conducted on twenty subjects suffering from recurrent cases of constipation, were administered 500 mg of MSM per day, along with 1 gram of ascorbic acid. All subjects with abnormal bowel functions have returned to a normal situation, which has lasted as long as they continued to take MSM.

Initially, with the recruitment of MSM some individuals may show some symptoms of detoxification, including mild forms of diarrhea, rashes, headache, fatigue states that generally disappear within a week.
There are no specific contraindications to the recruitment of MSM: the level of toxicity of MSM is among the lowest known, similar to that of water. An unpublished study conducted for six months from the Oregon Health Sciences University on Long-term toxicity of MSM, found no toxic effect. Within this study, more than 12,000 individuals who were administered 2 grams of MSM per day have not reported any side effects. It's was also noted that the effectiveness of MSM increases linked to vitamin C.

MSM

Main uses:

reported injuries and scarring due to accidents, burns, operations, repetitive strain (RSI) and sports (whiplash, tennis elbow, etc.).
osteoarthritis and rheumatoid arthritis
Fibromyalgia
lumbago
headache, migraine
muscle aches
bursitis
Carpal tunnel syndrome
sclerosis
asthma and allergies
Main actions:
analgesic, anti-inflammatory, detoxifying, vasodilator, muscle relaxants (muscle relaxant), immuno modulator, healing

Assay standards:
2-4 g twice daily

Contraindications:
None documented. MSM was one of the lowest known toxicity in biology and medicine, comparable to that of water. In any case:
It's been noticed a slight effect of fluidificazione blood, so it is recommended to patients with heart disease, careful monitoring.
It can cause detoxification reactions (including nausea, vomiting and diarrhea). If these reactions were to present to reduce or suspend its use for a few days.

Interaction with drugs:
None known.

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